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An Integrated Approach to Elucidate the Intra-Viral and Viral-Cellular Protein Interaction Networks of a Gamma-Herpesvirus

Genome-wide yeast two-hybrid (Y2H) screens were conducted to elucidate the molecular functions of open reading frames (ORFs) encoded by murine γ-herpesvirus 68 (MHV-68). A library of 84 MHV-68 genes and gene fragments was generated in a Gateway entry plasmid and transferred to Y2H vectors. All possi...

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Detalles Bibliográficos
Autores principales: Lee, Shaoying, Salwinski, Lukasz, Zhang, Chaoying, Chu, Derrick, Sampankanpanich, Claire, Reyes, Nichole A., Vangeloff, Abbey, Xing, Fangfang, Li, Xudong, Wu, Ting-Ting, Sahasrabudhe, Sudhir, Deng, Hongyu, LaCount, Douglas J., Sun, Ren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197595/
https://www.ncbi.nlm.nih.gov/pubmed/22028648
http://dx.doi.org/10.1371/journal.ppat.1002297