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Fitness Landscape of Antibiotic Tolerance in Pseudomonas aeruginosa Biofilms
Bacteria in biofilms have higher antibiotic tolerance than their planktonic counterparts. A major outstanding question is the degree to which the biofilm-specific cellular state and its constituent genetic determinants contribute to this hyper-tolerant phenotype. Here, we used genome-wide functional...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197603/ https://www.ncbi.nlm.nih.gov/pubmed/22028649 http://dx.doi.org/10.1371/journal.ppat.1002298 |