Tumor Suppressor Protein p53 Recruits Human Sin3B/HDAC1 Complex for Down-Regulation of Its Target Promoters in Response to Genotoxic Stress

Master regulator protein p53, popularly known as the “guardian of genome” is the hub for regulation of diverse cellular pathways. Depending on the cell type and severity of DNA damage, p53 protein mediates cell cycle arrest or apoptosis, besides activating DNA repair, which is apparently achieved by...

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Detalles Bibliográficos
Autores principales: Bansal, Nidhi, Kadamb, Rama, Mittal, Shilpi, Vig, Leena, Sharma, Raisha, Dwarakanath, Bilikere S., Saluja, Daman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197607/
https://www.ncbi.nlm.nih.gov/pubmed/22028823
http://dx.doi.org/10.1371/journal.pone.0026156

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197607/
https://www.ncbi.nlm.nih.gov/pubmed/22028823
http://dx.doi.org/10.1371/journal.pone.0026156

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