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Relationship between Localization on Cellular Membranes and Cytotoxicity of Vibrio vulnificus Hemolysin

Vibrio vulnificus secretes a hemolysin/cytolysin (VVH) that induces cytolysis in target cells. A detergent resistant membrane domain (DRM) fraction of the cells after sucrose gradient centrifugation includes cholesterol-rich membrane microdomains which have been called “lipid rafts”. It was reported...

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Detalles Bibliográficos
Autores principales: Sugiyama, Hiroyuki, Kashimoto, Takashige, Ueno, Shunji, Ehara, Hayato, Kodama, Toshio, Iida, Tetsuya, Susa, Nobuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197612/
https://www.ncbi.nlm.nih.gov/pubmed/22028805
http://dx.doi.org/10.1371/journal.pone.0026018