Novel Mouse Xenograft Models Reveal a Critical Role of CD4(+) T Cells in the Proliferation of EBV-Infected T and NK Cells

Epstein-Barr virus (EBV), a ubiquitous B-lymphotropic herpesvirus, ectopically infects T or NK cells to cause severe diseases of unknown pathogenesis, including chronic active EBV infection (CAEBV) and EBV-associated hemophagocytic lymphohistiocytosis (EBV-HLH). We developed xenograft models of CAEB...

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Detalles Bibliográficos
Autores principales: Imadome, Ken-Ichi, Yajima, Misako, Arai, Ayako, Nakazawa, Atsuko, Kawano, Fuyuko, Ichikawa, Sayumi, Shimizu, Norio, Yamamoto, Naoki, Morio, Tomohiro, Ohga, Shouichi, Nakamura, Hiroyuki, Ito, Mamoru, Miura, Osamu, Komano, Jun, Fujiwara, Shigeyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197618/
https://www.ncbi.nlm.nih.gov/pubmed/22028658
http://dx.doi.org/10.1371/journal.ppat.1002326

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197618/
https://www.ncbi.nlm.nih.gov/pubmed/22028658
http://dx.doi.org/10.1371/journal.ppat.1002326

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