A Semi-Quantitative, Synteny-Based Method to Improve Functional Predictions for Hypothetical and Poorly Annotated Bacterial and Archaeal Genes

During microbial evolution, genome rearrangement increases with increasing sequence divergence. If the relationship between synteny and sequence divergence can be modeled, gene clusters in genomes of distantly related organisms exhibiting anomalous synteny can be identified and used to infer functio...

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Detalles Bibliográficos
Autores principales: Yelton, Alexis P., Thomas, Brian C., Simmons, Sheri L., Wilmes, Paul, Zemla, Adam, Thelen, Michael P., Justice, Nicholas, Banfield, Jillian F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197636/
https://www.ncbi.nlm.nih.gov/pubmed/22028637
http://dx.doi.org/10.1371/journal.pcbi.1002230

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197636/
https://www.ncbi.nlm.nih.gov/pubmed/22028637
http://dx.doi.org/10.1371/journal.pcbi.1002230

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