The Leukemia-Specific Fusion Gene ETV6/RUNX1 Perturbs Distinct Key Biological Functions Primarily by Gene Repression

BACKGROUND: ETV6/RUNX1 (E/R) (also known as TEL/AML1) is the most frequent gene fusion in childhood acute lymphoblastic leukemia (ALL) and also most likely the crucial factor for disease initiation; its role in leukemia propagation and maintenance, however, remains largely elusive. To address this i...

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Detalles Bibliográficos
Autores principales: Fuka, Gerhard, Kauer, Maximilian, Kofler, Reinhard, Haas, Oskar A., Panzer-Grümayer, Renate
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197637/
https://www.ncbi.nlm.nih.gov/pubmed/22028862
http://dx.doi.org/10.1371/journal.pone.0026348

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197637/
https://www.ncbi.nlm.nih.gov/pubmed/22028862
http://dx.doi.org/10.1371/journal.pone.0026348

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