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Dynein Light Chain Tctex-Type 1 Modulates Orexin Signaling through Its Interaction with Orexin 1 Receptor

Orexins (OX-A, OX-B) are neuropeptides involved in the regulation of the sleep-wake cycle, feeding and reward, via activation of orexin receptors 1 and 2 (OX1R, OX2R). The loss of orexin peptides or functional OX2R has been shown to cause the sleep disorder, narcolepsy. Since the regulation of orexi...

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Detalles Bibliográficos
Autores principales: Duguay, David, Bélanger-Nelson, Erika, Mongrain, Valérie, Beben, Anna, Khatchadourian, Armen, Cermakian, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197643/
https://www.ncbi.nlm.nih.gov/pubmed/22028875
http://dx.doi.org/10.1371/journal.pone.0026430