Development and Inter-Laboratory Validation of Unlabeled Probe Melting Curve Analysis for Detection of JAK2 V617F Mutation in Polycythemia Vera

BACKGROUND: JAK2 V617F, a somatic point mutation that leads to constitutive JAK2 phosphorylation and kinase activation, has been incorporated into the WHO classification and diagnostic criteria of myeloid neoplasms. Although various approaches such as restriction fragment length polymorphism, amplif...

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Detalles Bibliográficos
Autores principales: Wu, Zhiyuan, Yuan, Hong, Zhang, Xinju, Liu, Weiwei, Xu, Jinhua, Zhang, Wei, Guan, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197667/
https://www.ncbi.nlm.nih.gov/pubmed/22028900
http://dx.doi.org/10.1371/journal.pone.0026534

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197667/
https://www.ncbi.nlm.nih.gov/pubmed/22028900
http://dx.doi.org/10.1371/journal.pone.0026534

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