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The Transcription Factors Snail and Slug Activate the Transforming Growth Factor-Beta Signaling Pathway in Breast Cancer

The transcriptional repressors Snail and Slug are situated at the core of several signaling pathways proposed to mediate epithelial to mesenchymal transition or EMT, which has been implicated in tumor metastasis. EMT involves an alteration from an organized, epithelial cell structure to a mesenchyma...

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Detalles Bibliográficos
Autores principales: Dhasarathy, Archana, Phadke, Dhiral, Mav, Deepak, Shah, Ruchir R., Wade, Paul A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197668/
https://www.ncbi.nlm.nih.gov/pubmed/22028892
http://dx.doi.org/10.1371/journal.pone.0026514