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The Transcription Factors Snail and Slug Activate the Transforming Growth Factor-Beta Signaling Pathway in Breast Cancer
The transcriptional repressors Snail and Slug are situated at the core of several signaling pathways proposed to mediate epithelial to mesenchymal transition or EMT, which has been implicated in tumor metastasis. EMT involves an alteration from an organized, epithelial cell structure to a mesenchyma...
Autores principales: | Dhasarathy, Archana, Phadke, Dhiral, Mav, Deepak, Shah, Ruchir R., Wade, Paul A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197668/ https://www.ncbi.nlm.nih.gov/pubmed/22028892 http://dx.doi.org/10.1371/journal.pone.0026514 |
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