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The carboxypeptidase angiotensin converting enzyme (ACE) shapes the MHC class I peptide repertoire
The surface presentation of peptides by major histocompatibility complex (MHC) class I molecules is critical to CD8(+) T cell mediated adaptive immune responses. Aminopeptidases are implicated in the editing of peptides for MHC class I loading, but C-terminal editing is thought due to proteasome cle...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197883/ https://www.ncbi.nlm.nih.gov/pubmed/21964607 http://dx.doi.org/10.1038/ni.2107 |