The carboxypeptidase angiotensin converting enzyme (ACE) shapes the MHC class I peptide repertoire

The surface presentation of peptides by major histocompatibility complex (MHC) class I molecules is critical to CD8(+) T cell mediated adaptive immune responses. Aminopeptidases are implicated in the editing of peptides for MHC class I loading, but C-terminal editing is thought due to proteasome cle...

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Detalles Bibliográficos
Autores principales: Shen, Xiao Z., Billet, Sandrine, Lin, Chentao, Okwan-Duodu, Derick, Chen, Xu, Lukacher, Aron E., Bernstein, Kenneth E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197883/
https://www.ncbi.nlm.nih.gov/pubmed/21964607
http://dx.doi.org/10.1038/ni.2107

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