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Therapeutic Potential of Nrf2 Activators in Streptozotocin-Induced Diabetic Nephropathy

OBJECTIVE: To determine whether dietary compounds targeting NFE2-related factor 2 (Nrf2) activation can be used to attenuate renal damage and preserve renal function during the course of streptozotocin (STZ)-induced diabetic nephropathy. RESEARCH DESIGN AND METHODS: Diabetes was induced in Nrf2(+/+)...

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Detalles Bibliográficos
Autores principales: Zheng, Hongting, Whitman, Samantha A., Wu, Wei, Wondrak, Georg T., Wong, Pak K., Fang, Deyu, Zhang, Donna D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198067/
https://www.ncbi.nlm.nih.gov/pubmed/22025779
http://dx.doi.org/10.2337/db11-0807