miR-146a–Mediated Extracellular Matrix Protein Production in Chronic Diabetes Complications

OBJECTIVE: microRNAs (miRNAs), through transcriptional regulation, modulate several cellular processes. In diabetes, increased extracellular matrix protein fibronectin (FN) production is known to occur through histone acetylator p300. Here, we investigated the role of miR-146a, an FN-targeting miRNA...

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Detalles Bibliográficos
Autores principales: Feng, Biao, Chen, Shali, McArthur, Kara, Wu, Yuexiu, Sen, Subhrojit, Ding, Qingming, Feldman, Ross D., Chakrabarti, Subrata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2011
Materias:
Complications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198068/
https://www.ncbi.nlm.nih.gov/pubmed/21885871
http://dx.doi.org/10.2337/db11-0478

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198068/
https://www.ncbi.nlm.nih.gov/pubmed/21885871
http://dx.doi.org/10.2337/db11-0478

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