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FoxO6 Integrates Insulin Signaling With Gluconeogenesis in the Liver

OBJECTIVE: Excessive endogenous glucose production contributes to fasting hyperglycemia in diabetes. This effect stems from inept insulin suppression of hepatic gluconeogenesis. To understand the underlying mechanisms, we studied the ability of forkhead box O6 (FoxO6) to mediate insulin action on he...

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Detalles Bibliográficos
Autores principales: Kim, Dae Hyun, Perdomo, German, Zhang, Ting, Slusher, Sandra, Lee, Sojin, Phillips, Brett E., Fan, Yong, Giannoukakis, Nick, Gramignoli, Roberto, Strom, Stephen, Ringquist, Steven, Dong, H. Henry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198083/
https://www.ncbi.nlm.nih.gov/pubmed/21940782
http://dx.doi.org/10.2337/db11-0548