Cargando…
FoxO6 Integrates Insulin Signaling With Gluconeogenesis in the Liver
OBJECTIVE: Excessive endogenous glucose production contributes to fasting hyperglycemia in diabetes. This effect stems from inept insulin suppression of hepatic gluconeogenesis. To understand the underlying mechanisms, we studied the ability of forkhead box O6 (FoxO6) to mediate insulin action on he...
Autores principales: | Kim, Dae Hyun, Perdomo, German, Zhang, Ting, Slusher, Sandra, Lee, Sojin, Phillips, Brett E., Fan, Yong, Giannoukakis, Nick, Gramignoli, Roberto, Strom, Stephen, Ringquist, Steven, Dong, H. Henry |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198083/ https://www.ncbi.nlm.nih.gov/pubmed/21940782 http://dx.doi.org/10.2337/db11-0548 |
Ejemplares similares
-
FoxO1 Links Insulin Resistance to Proinflammatory Cytokine IL-1β Production in Macrophages
por: Su, Dongming, et al.
Publicado: (2009) -
Preserved Energy Balance in Mice Lacking FoxO1 in Neurons of Nkx2.1 Lineage Reveals Functional Heterogeneity of FoxO1 Signaling Within the Hypothalamus
por: Heinrich, Garrett, et al.
Publicado: (2014) -
CREB and FoxO1: two transcription factors for the regulation of hepatic gluconeogenesis
por: Oh, Kyoung-Jin, et al.
Publicado: (2013) -
Suppression of FoxO1 Activity by Long-Chain Fatty Acyl Analogs
por: Zatara, Ghadeer, et al.
Publicado: (2011) -
Genome-wide analysis of FoxO1 binding in hepatic chromatin: Potential involvement of FoxO1 in linking retinoid signaling to hepatic gluconeogenesis
por: Shin, Dong-Ju, et al.
Publicado: (2012)