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Endothelial NO/cGMP/VASP Signaling Attenuates Kupffer Cell Activation and Hepatic Insulin Resistance Induced by High-Fat Feeding

OBJECTIVE: Proinflammatory activation of Kupffer cells is implicated in the effect of high-fat feeding to cause liver insulin resistance. We sought to determine whether reduced endothelial nitric oxide (NO) signaling contributes to the effect of high-fat feeding to increase hepatic inflammatory sign...

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Detalles Bibliográficos
Autores principales:	Tateya, Sanshiro, Rizzo, Norma O., Handa, Priya, Cheng, Andrew M., Morgan-Stevenson, Vicki, Daum, Guenter, Clowes, Alexander W., Morton, Gregory J., Schwartz, Michael W., Kim, Francis
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2011
Materias:	Signal Transduction
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198085/ https://www.ncbi.nlm.nih.gov/pubmed/21911751 http://dx.doi.org/10.2337/db11-0255

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