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Age- and Islet Autoimmunity–Associated Differences in Amino Acid and Lipid Metabolites in Children at Risk for Type 1 Diabetes

OBJECTIVE: Islet autoimmunity precedes type 1 diabetes and often initiates in childhood. Phenotypic variation in islet autoimmunity relative to the age of its development suggests heterogeneous mechanisms of autoimmune activation. To support this notion, we examined whether serum metabolite profiles...

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Detalles Bibliográficos
Autores principales: Pflueger, Maren, Seppänen-Laakso, Tuulikki, Suortti, Tapani, Hyötyläinen, Tuulia, Achenbach, Peter, Bonifacio, Ezio, Orešič, Matej, Ziegler, Anette-G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198092/
https://www.ncbi.nlm.nih.gov/pubmed/22025777
http://dx.doi.org/10.2337/db10-1652