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Targeting Curcusomes to Inflammatory Dendritic Cells Inhibits NF-κB and Improves Insulin Resistance in Obese Mice

OBJECTIVE: To determine whether and by what mechanism systemic delivery of curcumin-containing liposomes improves insulin resistance in the leptin deficient (ob/ob) mouse model of insulin resistance. RESEARCH DESIGN AND METHODS: Insulin resistant ob/ob mice with steatosis were injected intraperitone...

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Detalles Bibliográficos
Autores principales: Yekollu, Suman Kumar, Thomas, Ranjeny, O’Sullivan, Brendan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198103/
https://www.ncbi.nlm.nih.gov/pubmed/21885868
http://dx.doi.org/10.2337/db11-0275