The yeast Batten disease orthologue Btn1 controls endosome–Golgi retrograde transport via SNARE assembly

The human Batten disease gene CLN3 and yeast orthologue BTN1 encode proteins of unclear function. We show that the loss of BTN1 phenocopies that of BTN2, which encodes a retromer accessory protein involved in the retrieval of specific cargo from late endosomes (LEs) to the Golgi. However, Btn1 local...

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Detalles Bibliográficos
Autores principales: Kama, Rachel, Kanneganti, Vydehi, Ungermann, Christian, Gerst, Jeffrey E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198160/
https://www.ncbi.nlm.nih.gov/pubmed/21987636
http://dx.doi.org/10.1083/jcb.201102115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198160/
https://www.ncbi.nlm.nih.gov/pubmed/21987636
http://dx.doi.org/10.1083/jcb.201102115

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