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The yeast Batten disease orthologue Btn1 controls endosome–Golgi retrograde transport via SNARE assembly
The human Batten disease gene CLN3 and yeast orthologue BTN1 encode proteins of unclear function. We show that the loss of BTN1 phenocopies that of BTN2, which encodes a retromer accessory protein involved in the retrieval of specific cargo from late endosomes (LEs) to the Golgi. However, Btn1 local...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198160/ https://www.ncbi.nlm.nih.gov/pubmed/21987636 http://dx.doi.org/10.1083/jcb.201102115 |