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Energy determinants GAPDH and NDPK act as genetic modifiers for hepatocyte inclusion formation

Genetic factors impact liver injury susceptibility and disease progression. Prominent histological features of some chronic human liver diseases are hepatocyte ballooning and Mallory-Denk bodies. In mice, these features are induced by 3,5-diethoxycarbonyl-1,4-dihydrocollidine (DDC) in a strain-depen...

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Detalles Bibliográficos
Autores principales: Snider, Natasha T., Weerasinghe, Sujith V.W., Singla, Amika, Leonard, Jessica M., Hanada, Shinichiro, Andrews, Philip C., Lok, Anna S., Omary, M. Bishr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198167/
https://www.ncbi.nlm.nih.gov/pubmed/22006949
http://dx.doi.org/10.1083/jcb.201102142