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High-resolution imaging reveals indirect coordination of opposite motors and a role for LIS1 in high-load axonal transport
The specific physiological roles of dynein regulatory factors remain poorly understood as a result of their functional complexity and the interdependence of dynein and kinesin motor activities. We used a novel approach to overcome these challenges, combining acute in vivo inhibition with automated h...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198168/ https://www.ncbi.nlm.nih.gov/pubmed/22006948 http://dx.doi.org/10.1083/jcb.201104076 |