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Comparison of D(2) dopamine receptor occupancy after oral administration of quetiapine fumarate immediate-release and extended-release formulations in healthy subjects

Quetiapine is an established drug for treatment of schizophrenia, bipolar disorder, and major depressive disorder. While initially manufactured as an immediate-release (IR) formulation, an extended-release (XR) formulation has recently been introduced. Pharmacokinetic studies show that quetiapine XR...

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Detalles Bibliográficos
Autores principales: Nord, Magdalena, Nyberg, Svante, Brogren, Jacob, Jucaite, Aurelija, Halldin, Christer, Farde, Lars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198174/
https://www.ncbi.nlm.nih.gov/pubmed/21477416
http://dx.doi.org/10.1017/S1461145711000514