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Comparison of D(2) dopamine receptor occupancy after oral administration of quetiapine fumarate immediate-release and extended-release formulations in healthy subjects
Quetiapine is an established drug for treatment of schizophrenia, bipolar disorder, and major depressive disorder. While initially manufactured as an immediate-release (IR) formulation, an extended-release (XR) formulation has recently been introduced. Pharmacokinetic studies show that quetiapine XR...
Autores principales: | Nord, Magdalena, Nyberg, Svante, Brogren, Jacob, Jucaite, Aurelija, Halldin, Christer, Farde, Lars |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cambridge University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198174/ https://www.ncbi.nlm.nih.gov/pubmed/21477416 http://dx.doi.org/10.1017/S1461145711000514 |
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