Cargando…

Filamin depletion blocks endoplasmic spreading and destabilizes force-bearing adhesions

Cell motility is an essential process that depends on a coherent, cross-linked actin cytoskeleton that physically coordinates the actions of numerous structural and signaling molecules. The actin cross-linking protein, filamin (Fln), has been implicated in the support of three-dimensional cortical a...

Descripción completa

Detalles Bibliográficos
Autores principales: Lynch, Christopher D., Gauthier, Nils C., Biais, Nicolas, Lazar, Andre M., Roca-Cusachs, Pere, Yu, Cheng-Han, Sheetz, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198308/
https://www.ncbi.nlm.nih.gov/pubmed/21325628
http://dx.doi.org/10.1091/mbc.E10-08-0661