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Mechanism of Disruption of the Amt-GlnK Complex by P(II)-Mediated Sensing of 2-Oxoglutarate
GlnK proteins regulate the active uptake of ammonium by Amt transport proteins by inserting their regulatory T-loops into the transport channels of the Amt trimer and physically blocking substrate passage. They sense the cellular nitrogen status through 2-oxoglutarate, and the energy level of the ce...
Autores principales: | Maier, Sarah, Schleberger, Paula, Lü, Wei, Wacker, Tobias, Pflüger, Tobias, Litz, Claudia, Andrade, Susana L. A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198391/ https://www.ncbi.nlm.nih.gov/pubmed/22039461 http://dx.doi.org/10.1371/journal.pone.0026327 |
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