Promoter Hypermethylation Mediated Downregulation of FBP1 in Human Hepatocellular Carcinoma and Colon Cancer

FBP1, fructose-1,6-bisphosphatase-1, a gluconeogenesis regulatory enzyme, catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate. The mechanism that it functions to antagonize glycolysis and was epigenetically inactivated through NF-kappaB pathway in ga...

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Detalles Bibliográficos
Autores principales: Chen, Mingquan, Zhang, Jianbin, Li, Ning, Qian, Zhiping, Zhu, Mengqi, Li, Qian, Zheng, Jianming, Wang, Xinyu, Shi, Guangfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198434/
https://www.ncbi.nlm.nih.gov/pubmed/22039417
http://dx.doi.org/10.1371/journal.pone.0025564

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198434/
https://www.ncbi.nlm.nih.gov/pubmed/22039417
http://dx.doi.org/10.1371/journal.pone.0025564

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