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Promoter Hypermethylation Mediated Downregulation of FBP1 in Human Hepatocellular Carcinoma and Colon Cancer

FBP1, fructose-1,6-bisphosphatase-1, a gluconeogenesis regulatory enzyme, catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate. The mechanism that it functions to antagonize glycolysis and was epigenetically inactivated through NF-kappaB pathway in ga...

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Detalles Bibliográficos
Autores principales:	Chen, Mingquan, Zhang, Jianbin, Li, Ning, Qian, Zhiping, Zhu, Mengqi, Li, Qian, Zheng, Jianming, Wang, Xinyu, Shi, Guangfeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198434/ https://www.ncbi.nlm.nih.gov/pubmed/22039417 http://dx.doi.org/10.1371/journal.pone.0025564

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