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miRNA Regulatory Circuits in ES Cells Differentiation: A Chemical Kinetics Modeling Approach

MicroRNAs (miRNAs) play an important role in gene regulation for Embryonic Stem cells (ES cells), where they either down-regulate target mRNA genes by degradation or repress protein expression of these mRNA genes by inhibiting translation. Well known tables TargetScan and miRanda may predict quite l...

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Detalles Bibliográficos
Autores principales: Luo, Zijun, Xu, Xuping, Gu, Peili, Lonard, David, Gunaratne, Preethi H., Cooney, Austin J., Azencott, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198445/
https://www.ncbi.nlm.nih.gov/pubmed/22039400
http://dx.doi.org/10.1371/journal.pone.0023263