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Molecular Basis of Bcl-X(L)-p53 Interaction: Insights from Molecular Dynamics Simulations
Bcl-X(L), an antiapoptotic Bcl-2 family protein, plays a central role in the regulation of the apoptotic pathway. Heterodimerization of the antiapoptotic Bcl-2 family proteins with the proapoptotic family members such as Bad, Bak, Bim and Bid is a crucial step in the apoptotic regulation. In additio...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198449/ https://www.ncbi.nlm.nih.gov/pubmed/22039431 http://dx.doi.org/10.1371/journal.pone.0026014 |