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Warfarin Anticoagulation Exacerbates the Risk of Hemorrhagic Transformation after rt-PA Treatment in Experimental Stroke: Therapeutic Potential of PCC

BACKGROUND: Oral anticoagulant therapy (OAT) with warfarin is the standard of stroke prevention in patients with atrial fibrillation. Approximately 30% of patients with cardioembolic strokes are on OAT at the time of symptom onset. We investigated whether warfarin exacerbates the risk of thrombolysi...

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Detalles Bibliográficos
Autores principales: Pfeilschifter, Waltraud, Spitzer, Daniel, Pfeilschifter, Josef, Steinmetz, Helmuth, Foerch, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198453/
https://www.ncbi.nlm.nih.gov/pubmed/22039437
http://dx.doi.org/10.1371/journal.pone.0026087