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Systematic Analysis of Gene Expression Differences between Left and Right Atria in Different Mouse Strains and in Human Atrial Tissue

BACKGROUND: Normal development of the atria requires left-right differentiation during embryonic development. Reduced expression of Pitx2c (paired-like homeodomain transcription factor 2, isoform c), a key regulator of left-right asymmetry, has recently been linked to atrial fibrillation. We therefo...

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Detalles Bibliográficos
Autores principales: Kahr, Peter C., Piccini, Ilaria, Fabritz, Larissa, Greber, Boris, Schöler, Hans, Scheld, Hans H., Hoffmeier, Andreas, Brown, Nigel A., Kirchhof, Paulus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198471/
https://www.ncbi.nlm.nih.gov/pubmed/22039477
http://dx.doi.org/10.1371/journal.pone.0026389