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RMRP Is a Non-Coding RNA Essential for Early Murine Development

RMRP is a non-coding RNA that is ubiquitously expressed in both humans and mice. RMRP mutations that lead to decreased RMRP levels are found in the pleiotropic syndrome Cartilage Hair Hypoplasia. To assess the effects of deleting RMRP, we engineered a targeting vector that contains loxP sequences fl...

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Detalles Bibliográficos
Autores principales: Rosenbluh, Joseph, Nijhawan, Deepak, Chen, Zhao, Wong, Kwok-Kin, Masutomi, Kenkichi, Hahn, William C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198473/
https://www.ncbi.nlm.nih.gov/pubmed/22039455
http://dx.doi.org/10.1371/journal.pone.0026270