Cargando…

RMRP Is a Non-Coding RNA Essential for Early Murine Development

RMRP is a non-coding RNA that is ubiquitously expressed in both humans and mice. RMRP mutations that lead to decreased RMRP levels are found in the pleiotropic syndrome Cartilage Hair Hypoplasia. To assess the effects of deleting RMRP, we engineered a targeting vector that contains loxP sequences fl...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rosenbluh, Joseph, Nijhawan, Deepak, Chen, Zhao, Wong, Kwok-Kin, Masutomi, Kenkichi, Hahn, William C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198473/ https://www.ncbi.nlm.nih.gov/pubmed/22039455 http://dx.doi.org/10.1371/journal.pone.0026270

Ejemplares similares

Off-Target Effect of Endogenous siRNA Derived from RMRP in Human Cells
por: Maida, Yoshiko, et al.
Publicado: (2013)

Long Non-coding RNA RMRP in the Pathogenesis of Human Disorders
por: Hussen, Bashdar Mahmud, et al.
Publicado: (2021)

Long Non-Coding RNA RMRP Contributes to Sepsis-Induced Acute Kidney Injury
por: Zhang, Xia, et al.
Publicado: (2021)

LncRNA-RMRP Acts as an Oncogene in Lung Cancer
por: Meng, Qingjun, et al.
Publicado: (2016)

Up-regulation of the long non-coding RNA RMRP contributes to glioma progression and promotes glioma cell proliferation and invasion
por: Feng, Wenxian, et al.
Publicado: (2017)

RMRP, RMST, FTX and IPW: novel potential long non-coding RNAs in medullary thyroid cancer
por: Luzón-Toro, Berta, et al.
Publicado: (2021)

The human long non-coding RNA gene RMRP has pleiotropic effects and regulates cell-cycle progression at G2
por: Vakkilainen, Svetlana, et al.
Publicado: (2019)

MicroRNA-675 directly targets MAPK1 to suppress the oncogenicity of papillary thyroid cancer and is sponged by long non-coding RNA RMRP
por: Wang, Junyi, et al.
Publicado: (2019)

MicroRNA-675 Directly Targets MAPK1 to Suppress the Oncogenicity of Papillary Thyroid Cancer and is Sponged by Long Non-Coding RNA RMRP [Retraction]
Publicado: (2021)

Expression of RMRP RNA is regulated in chondrocyte hypertrophy and determines chondrogenic differentiation
por: Steinbusch, Mandy M. F., et al.
Publicado: (2017)

Inactivation of the tumor suppressor p53 by long noncoding RNA RMRP
por: Chen, Yajie, et al.
Publicado: (2021)

The emerging role of long noncoding RNA RMRP in cancer development and targeted therapy
por: Hao, Qian, et al.
Publicado: (2022)

Evolutionary Comparison Provides Evidence for Pathogenicity of RMRP Mutations
por: Bonafé, Luisa, et al.
Publicado: (2005)

Widespread association of ERα with RMRP and tRNA genes in MCF-7 cells and breast cancers
por: Malcolm, Jodie R., et al.
Publicado: (2022)

Long Noncoding RNA RMRP Suppresses the Tumorigenesis of Hepatocellular Carcinoma Through Targeting microRNA-766
por: Shao, Cunhua, et al.
Publicado: (2020)

An RNA dependent RNA polymerase formed by hTERT and the RNase MRP RNA
por: Maida, Yoshiko, et al.
Publicado: (2009)

Telomerase reverse transcriptase moonlights: Therapeutic targets beyond telomerase
por: Maida, Yoshiko, et al.
Publicado: (2015)

HuR and GRSF1 modulate the nuclear export and mitochondrial localization of the lncRNA RMRP
por: Noh, Ji Heon, et al.
Publicado: (2016)

Upregulation of lncRNA RMRP promotes the activation of cardiac fibroblasts by regulating miR-613
por: Zhang, Shuang-Yin, et al.
Publicado: (2019)

The long noncoding RNA of RMRP is downregulated by PERK, which induces apoptosis in hepatocellular carcinoma cells
por: Yukimoto, Atsushi, et al.
Publicado: (2021)

Semi-quantitative Detection of RNA-dependent RNA Polymerase Activity of Human Telomerase Reverse Transcriptase Protein
por: Maida, Yoshiko, et al.
Publicado: (2018)

RNA‐dependent RNA polymerase, RdRP, a promising therapeutic target for cancer and potentially COVID‐19
por: Machitani, Mitsuhiro, et al.
Publicado: (2020)

DDX5 and its associated lncRNA Rmrp modulate Th17 cell effector functions
por: Huang, Wendy, et al.
Publicado: (2015)

LncRNA‐RMRP promotes nucleus pulposus cell proliferation through regulating miR‐206 expression
por: Wang, Xuesong, et al.
Publicado: (2018)

Metaphyseal Dysplasia Without Hypotrichosis Caused by RNA Component of Mitochondrial RNA-Processing Endoribonuclease (RMRP) Gene Variants: The First Case in Korea
por: Namgoong, Ho, et al.
Publicado: (2021)

LncRNA RMRP Promotes Cell Proliferation and Invasion Through miR-613/NFAT5 Axis in Non-Small Cell Lung Cancer
por: Yang, Mingjun, et al.
Publicado: (2020)

LncRNA-RMRP promotes carcinogenesis by acting as a miR-206 sponge and is used as a novel biomarker for gastric cancer
por: Shao, Yongfu, et al.
Publicado: (2016)

A potential synthetic lethal strategy with PARP inhibitors: perspective on ‘Inactivation of the tumor suppressor p53 by long noncoding RNA RMRP’
por: Hao, Qian, et al.
Publicado: (2021)

Long Noncoding RNA RMRP Contributes to Paclitaxel Sensitivity of Ovarian Cancer by Regulating miR-580-3p/MICU1 Signaling
por: Li, Lingling, et al.
Publicado: (2022)

Homozygous RMRP Promoter Duplications Cause Severely Reduced Transcript Abundance and SCID Associated with Cartilage Hair Hypoplasia
por: Tan, Ryan, et al.
Publicado: (2023)

Comparison of telomere length and association with progenitor cell markers in lacrimal gland between Sjögren syndrome and non-Sjögren syndrome dry eye patients
por: Kawashima, Motoko, et al.
Publicado: (2011)

A positive feedback loop of lncRNA-RMRP/ZNRF3 axis and Wnt/β-catenin signaling regulates the progression and temozolomide resistance in glioma
por: Liu, Tie, et al.
Publicado: (2021)

Two-step cleavage of hairpin RNA with 5' overhangs by human DICER
por: Ando, Yoshinari, et al.
Publicado: (2011)

Eribulin Mesylate Targets Human Telomerase Reverse Transcriptase in Ovarian Cancer Cells
por: Yamaguchi, Satoko, et al.
Publicado: (2014)

The H19 Non-Coding RNA Is Essential for Human Tumor Growth
por: Matouk, Imad J., et al.
Publicado: (2007)

Non-Coding RNA Databases in Cardiovascular Research
por: Balamurali, Deepak, et al.
Publicado: (2020)

lncRNA RMRP predicts poor prognosis and mediates tumor progression of esophageal squamous cell carcinoma by regulating miR-613/ neuropilin 2 (NRP2) axis
por: Xie, Zhen, et al.
Publicado: (2021)

Non-Coding RNA-Based Biosensors for Early Detection of Liver Cancer
por: Falahi, Sedigheh, et al.
Publicado: (2021)

The long non-coding RNA SAMMSON is essential for uveal melanoma cell survival
por: Dewaele, Shanna, et al.
Publicado: (2021)

Murine Surf4 is essential for early embryonic development
por: Emmer, Brian T., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_i9elrehkj9vi4o56h296gt3p04