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Activity of Ca(2+) -activated Cl(-) channels contributes to regulating receptor- and store-operated Ca(2+) entry in human pulmonary artery smooth muscle cells

Intracellular Ca(2+) plays a fundamental role in regulating cell functions in pulmonary arterial smooth muscle cells (PASMCs). A rise in cytosolic Ca(2+) concentration ([Ca(2+)](cyt)) triggers pulmonary vasoconstriction and stimulates PASMC proliferation. [Ca(2+)](cyt) is increased mainly by Ca(2+)...

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Detalles Bibliográficos
Autores principales: Yamamura, Aya, Yamamura, Hisao, Zeifman, Amy, Yuan, Jason X.-J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198647/
https://www.ncbi.nlm.nih.gov/pubmed/22034612
http://dx.doi.org/10.4103/2045-8932.83447