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Nck2 promotes human melanoma cell proliferation, migration and invasion in vitro and primary melanoma-derived tumor growth in vivo

BACKGROUND: Nck1 and Nck2 adaptor proteins are involved in signaling pathways mediating proliferation, cytoskeleton organization and integrated stress response. Overexpression of Nck1 in fibroblasts has been shown to be oncogenic. Through the years this concept has been challenged and the consensus...

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Detalles Bibliográficos
Autores principales: Labelle-Côté, Mélissa, Dusseault, Julie, Ismaïl, Salma, Picard-Cloutier, Aude, Siegel, Peter M, Larose, Louise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198724/
https://www.ncbi.nlm.nih.gov/pubmed/21992144
http://dx.doi.org/10.1186/1471-2407-11-443