GABA Coordinates with Insulin in Regulating Secretory Function in Pancreatic INS-1 β-Cells

Pancreatic islet β-cells produce large amounts of γ-aminobutyric acid (GABA), which is co-released with insulin. GABA inhibits glucagon secretion by hyperpolarizing α-cells via type-A GABA receptors (GABA(A)Rs). We and others recently reported that islet β-cells also express GABA(A)Rs and that activ...

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Detalles Bibliográficos
Autores principales: Bansal, Paul, Wang, Shuanglian, Liu, Shenghao, Xiang, Yun-Yan, Lu, Wei-Yang, Wang, Qinghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198728/
https://www.ncbi.nlm.nih.gov/pubmed/22031825
http://dx.doi.org/10.1371/journal.pone.0026225

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198728/
https://www.ncbi.nlm.nih.gov/pubmed/22031825
http://dx.doi.org/10.1371/journal.pone.0026225

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