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Hypothalamic Obesity following Craniopharyngioma Surgery: Results of a Pilot Trial of Combined Diazoxide and Metformin Therapy

Objective. To assess the effect of combined diazoxide-metformin therapy in obese adolescents treated for craniopharyngioma. Design. A prospective open-label 6-month pilot treatment trial in 9 obese subjects with craniopharyngioma. Diazoxide (2 mg/kg divided b.i.d., maximum 200 mg/day) and metformin...

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Detalles Bibliográficos
Autores principales: Hamilton, JillK, Conwell, LouiseS, Syme, Catriona, Ahmet, Alexandra, Jeffery, Allison, Daneman, Denis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198743/
https://www.ncbi.nlm.nih.gov/pubmed/21603206
http://dx.doi.org/10.1155/2011/417949