Appetite for destruction: the inhibition of glycolysis as a therapy for tuberous sclerosis complex-related tumors

The elevated metabolic requirements of cancer cells reflect their rapid growth and proliferation and are met through mutations in oncogenes and tumor suppressor genes that reprogram cellular processes. For example, in tuberous sclerosis complex (TSC)-related tumors, the loss of TSC1/2 function cause...

Descripción completa

Detalles Bibliográficos
Autores principales: Csibi, Alfredo, Blenis, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198763/
https://www.ncbi.nlm.nih.gov/pubmed/22018140
http://dx.doi.org/10.1186/1741-7007-9-69

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198763/
https://www.ncbi.nlm.nih.gov/pubmed/22018140
http://dx.doi.org/10.1186/1741-7007-9-69

Ejemplares similares