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Appetite for destruction: the inhibition of glycolysis as a therapy for tuberous sclerosis complex-related tumors
The elevated metabolic requirements of cancer cells reflect their rapid growth and proliferation and are met through mutations in oncogenes and tumor suppressor genes that reprogram cellular processes. For example, in tuberous sclerosis complex (TSC)-related tumors, the loss of TSC1/2 function cause...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198763/ https://www.ncbi.nlm.nih.gov/pubmed/22018140 http://dx.doi.org/10.1186/1741-7007-9-69 |