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Hydroxyfasudil-Mediated Inhibition of ROCK1 and ROCK2 Improves Kidney Function in Rat Renal Acute Ischemia-Reperfusion Injury

Renal ischemia-reperfusion (IR) injury (IRI) is a common and important trigger of acute renal injury (AKI). It is inevitably linked to transplantation. Involving both, the innate and the adaptive immune response, IRI causes subsequent sterile inflammation. Attraction to and transmigration of immune...

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Detalles Bibliográficos
Autores principales: Kentrup, Dominik, Reuter, Stefan, Schnöckel, Uta, Grabner, Alexander, Edemir, Bayram, Pavenstädt, Hermann, Schober, Otmar, Schäfers, Michael, Schlatter, Eberhard, Büssemaker, Eckhart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198766/
https://www.ncbi.nlm.nih.gov/pubmed/22031832
http://dx.doi.org/10.1371/journal.pone.0026419