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Hydroxyfasudil-Mediated Inhibition of ROCK1 and ROCK2 Improves Kidney Function in Rat Renal Acute Ischemia-Reperfusion Injury
Renal ischemia-reperfusion (IR) injury (IRI) is a common and important trigger of acute renal injury (AKI). It is inevitably linked to transplantation. Involving both, the innate and the adaptive immune response, IRI causes subsequent sterile inflammation. Attraction to and transmigration of immune...
Autores principales: | Kentrup, Dominik, Reuter, Stefan, Schnöckel, Uta, Grabner, Alexander, Edemir, Bayram, Pavenstädt, Hermann, Schober, Otmar, Schäfers, Michael, Schlatter, Eberhard, Büssemaker, Eckhart |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198766/ https://www.ncbi.nlm.nih.gov/pubmed/22031832 http://dx.doi.org/10.1371/journal.pone.0026419 |
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