LL37 and Cationic Peptides Enhance TLR3 Signaling by Viral Double-stranded RNAs

BACKGROUND: Toll-like Receptor 3 (TLR3) detects viral dsRNA during viral infection. However, most natural viral dsRNAs are poor activators of TLR3 in cell-based systems, leading us to hypothesize that TLR3 needs additional factors to be activated by viral dsRNAs. The anti-microbial peptide LL37 is t...

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Detalles Bibliográficos
Autores principales: Lai, Yvonne, Adhikarakunnathu, Sreedevi, Bhardwaj, Kanchan, Ranjith-Kumar, C. T., Wen, Yahong, Jordan, Jarrat L., Wu, Linda H., Dragnea, Bogdan, Mateo, Lani San, Kao, C. Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198786/
https://www.ncbi.nlm.nih.gov/pubmed/22039520
http://dx.doi.org/10.1371/journal.pone.0026632

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198786/
https://www.ncbi.nlm.nih.gov/pubmed/22039520
http://dx.doi.org/10.1371/journal.pone.0026632

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