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piggyBac Transposon Somatic Mutagenesis with an Activated Reporter and Tracker (PB-SMART) for Genetic Screens in Mice

Somatic forward genetic screens have the power to interrogate thousands of genes in a single animal. Retroviral and transposon mutagenesis systems in mice have been designed and deployed in somatic tissues for surveying hematopoietic and solid tumor formation. In the context of cancer, the ability t...

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Detalles Bibliográficos
Autores principales: Landrette, Sean F., Cornett, Jonathan C., Ni, Thomas K., Bosenberg, Marcus W., Xu, Tian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198810/
https://www.ncbi.nlm.nih.gov/pubmed/22039523
http://dx.doi.org/10.1371/journal.pone.0026650