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EGFR-specific T cell frequencies correlate with EGFR expression in head and neck squamous cell carcinoma

BACKGROUND: In head and neck squamous cell carcinoma (HNSCC), expression levels of the epidermal growth factor receptor (EGFR) correlate with poor prognosis and decreased survival rates. As the mechanisms responsible for cellular immune response to EGFR in vivo remain unclear, the frequency and func...

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Detalles Bibliográficos
Autores principales: Schuler, Patrick J, Boeckers, Petra, Engers, Rainer, Boelke, Edwin, Bas, Murat, Greve, Jens, Dumitru, Claudia A, Lehnerdt, Goetz F, Ferris, Robert L, Andrade Filho, Pedro A, Brandau, Sven, Lang, Stephan, Whiteside, Theresa L, Hoffmann, Thomas K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198929/
https://www.ncbi.nlm.nih.gov/pubmed/21970318
http://dx.doi.org/10.1186/1479-5876-9-168