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Myocardin-Related Transcription Factors-A and -B are Key Regulators of TGF-β1-Induced Fibroblast to Myofibroblast Differentiation

Myofibroblasts are contractile, smooth muscle-like cells that are characterized by the de novo expression of smooth muscle α-actin (SMαA) and normally function to assist in wound closure, but have been implicated in pathological contractures. Transforming growth factor beta-1 (TGF-β1) helps facilita...

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Detalles Bibliográficos
Autores principales: Crider, Beverly J., Risinger, George M., Haaksma, Carol J., Howard, Eric W., Tomasek, James J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3199034/
https://www.ncbi.nlm.nih.gov/pubmed/21776010
http://dx.doi.org/10.1038/jid.2011.219