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Myocardin-Related Transcription Factors-A and -B are Key Regulators of TGF-β1-Induced Fibroblast to Myofibroblast Differentiation
Myofibroblasts are contractile, smooth muscle-like cells that are characterized by the de novo expression of smooth muscle α-actin (SMαA) and normally function to assist in wound closure, but have been implicated in pathological contractures. Transforming growth factor beta-1 (TGF-β1) helps facilita...
Autores principales: | Crider, Beverly J., Risinger, George M., Haaksma, Carol J., Howard, Eric W., Tomasek, James J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3199034/ https://www.ncbi.nlm.nih.gov/pubmed/21776010 http://dx.doi.org/10.1038/jid.2011.219 |
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