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Systemic Administration of CpG Oligodeoxynucleotide and Levamisole as Adjuvants for Gene-Gun-Delivered Antitumor DNA Vaccines

DNA vaccines showed great promise in preclinical models of infectious and malignant diseases, but their potency was insufficient in clinical trials and is needed to be improved. In this study, we tested systemic administration of two conventional adjuvants, synthetic oligodeoxynucleotide carrying im...

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Detalles Bibliográficos
Autores principales: Šmahel, Michal, Poláková, Ingrid, Sobotková, Eva, Vajdová, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3199051/
https://www.ncbi.nlm.nih.gov/pubmed/22028727
http://dx.doi.org/10.1155/2011/176759